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NRC-AN-019是Bcr-Abl蛋白-酪氨酸激酶的口服酪氨酸激酶抑制剂（TKI）。NRC-AN-019在抑制MDAMB231和HTB20/BT474细胞的血管生成潜力和增殖方面更有效。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.33 mL | 96.63 mL | 193.26 mL |
| 0.5 mM | 3.87 mL | 19.33 mL | 38.65 mL |
| 1 mM | 1.93 mL | 9.66 mL | 19.33 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.87 mL |
*The above data is based on the productmolecular weight 517.431. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13562 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 517.431 |
| Formula | C25H17F6N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 879507-25-2 |
| Synonyms | AN019, AN 019, NRC-an-019 |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)NC3=NC=CC(=N3)C4=CN=CC=C4 |
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