产品详情

生物活性

NS-398是具有镇痛和解热作用的非甾体类抗炎药，可选择性抑制前列腺素G / H合酶2 /环氧合酶2（COX-2）活性，IC50为3.8μM，对COX无影响

靶点信息

溶解度 *

In vitro	DMSO	53 mg/mL (168.59 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.81 mL	159.05 mL	318.11 mL
0.5 mM	6.36 mL	31.81 mL	63.62 mL
1 mM	3.18 mL	15.91 mL	31.81 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

*The above data is based on the productmolecular weight 314.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13116
作用机制	Inhibitor (抑制剂)
M. Wt	314.36
Formula	C13H18N2O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	123653-11-2
Synonyms	NS398, NS 398
SMILES	CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2