Kittaka M, .et al. , J Bone Miner Res, 2018, Jan;33(1):167-181 PMID: 28914985
生物活性
Discription
NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).
Targets
Target
Value
产品信息
目录号
A13072
分子式
C12H15Cl2NO
分子量
260.16
CAS号
CAS: 7497-07-6
SMILES
CCCC(C)NC(=O)C1=CC(=C(C=C1)Cl)Cl
其他名称
NSC405020, NSC-405020
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro (25°C)
DMSO
48 mg/mL (184.5 mM)
Water
Insoluble
Ethanol
48 mg/mL (184.5 mM)
In vivo
1% DMSO+30% polyethylene glycol+1% Tween 80
4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: