NSC-703786 (5F-203)
目录号: A22708
NSC-703786(5F-203)是一种细胞毒性分子,能形成DNA加合物从而导致细胞死亡。NSC-703786诱导芳香烃受体信号传导,并提高CYP1A1的表达。用NSC-703786处理细胞还会导致活性氧的增加以及p38、JNK和ERK的激活。
Discription | NSC-703786 (5F-203) is a cytotoxic molecule that forms DNA adducts leading to cell death. NSC-703786 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with NSC-703786 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK. |
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目录号 | A22708 |
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分子式 | C14H11FN2S |
分子量 | 258.3 |
CAS号 | 260443-89-8 |
SMILES | FC1=CC=C(SC(C2=CC=C(N)C(C)=C2)=N3)C3=C1 |
其他名称 | 5-fluoro 203, NSC703786, NSC 703786 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2