NSC348884
目录号: A13117
nucleophosmin 抑制剂
NSC348884 是一种核仁磷酸蛋白，具有多种生物活性，包括核糖体生物生成、细胞增殖、细胞质/核穿梭运输、核酸结合、核糖核酸切割和中心体复制。NSC 348884 是一种假定的核磷蛋白（NPM）抑制剂。NSC 348884 抑制 NMP 寡聚体形成，上调 p53 并诱导凋亡。
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生物活性
| Discription | NSC348884 is a nucleolar phosphoprotein that displays several biological activities in ribosome biogenesis, cell proliferation, cytoplasmic/nuclear shuttle transportation, nucleic acid binding, ribonucleic cleavage, and centrosome duplication. NSC 348884 is a putative inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53 and induces apoptosis. | ||
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产品信息
| 目录号 | A13117 |
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| 分子式 | C38H40N10 |
| 分子量 | 636.79 |
| CAS号 | 81624-55-7 |
| SMILES | CC1=CC2=C(C=C1)N=C(N2)CN(CCN(CC3=NC4=C(N3)C=C(C=C4)C)CC5=NC6=C(N5)C=C(C=C6)C)CC7=NC8=C(N7)C=C(C=C8)C |
| 其他名称 | NSC 348884, NSC-348884 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 92 mg/mL (144.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 92 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.7 mL | 78.52 mL | 157.04 mL |
| 0.5 mM | 3.14 mL | 15.7 mL | 31.41 mL |
| 1 mM | 1.57 mL | 7.85 mL | 15.7 mL |
| 5 mM | 0.31 mL | 1.57 mL | 3.14 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 81624-55-7 | 81624-55-7 供应商 | 81624-55-7 花费 | 81624-55-7 生产商 | 订购 81624-55-7 | 81624-55-7 代理商