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Nutlin-3

目录号: A10657
Mdm2 拮抗剂
MDM2拮抗剂nutlin-3是一种强效的凋亡诱导剂。
Grouped product items
规格 价格 库存 数量
2mg
¥315.00
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5mg
¥420.00
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10mg
¥770.00
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25mg
¥1,365.00
现货
50mg
¥2,485.00
现货
100mg
¥3,605.00
现货
10mM * 1mL in DMSO
¥735.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Nutlin-3发表的4篇文献
  • Maxime Parisotto, .et al. , J Exp Med, 2018, Jun 4; 215(6): 1749-1763 PMID: 29743291
  • Ohmuro-Matsuyama Y, .et al. , Anal Biochem, 2018, Dec 15;563:61-66 PMID: 30316750
  • Alisa A. Garaeva, .et al. , Cell Cycle, 2016, 15(1): 64-71 PMID: 26771712
  • A G Evstafieva, .et al. , Cell Death Dis., 2014, 5(11): e1511. PMID: 25375376
  • 生物活性
    Discription MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
    产品信息
    目录号 A10657
    分子式 C30H30Cl2N4O4
    分子量 581.5
    CAS号 548472-68-0
    SMILES CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 87 mg/mL (149.61 mM)
    Water Insoluble
    Ethanol 26 mg/mL (44.71 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.2 mL 85.98 mL 171.97 mL
    0.5 mM 3.44 mL 17.2 mL 34.39 mL
    1 mM 1.72 mL 8.6 mL 17.2 mL
    5 mM 0.34 mL 1.72 mL 3.44 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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