NVP-BGT226
目录号: A11162
PI3K 抑制剂
NVP-BGT226，一种新型的磷脂酰肌醇3激酶/mTOR双重抑制剂，在体外和体内对人类头颈癌细胞显示出强大的生长抑制活性。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | NVP-BGT226, novel phosphoinositide 3-kinase/mTOR dual inhibitor, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo. |
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产品信息
| 目录号 | A11162 |
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| 分子式 | C28H25F3N6O2.C4H4O4 |
| 分子量 | 650.6 |
| CAS号 | 1245537-68-1 |
| SMILES | CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=C\C(=O)O)\C(=O)O |
| 其他名称 | NVPBGT226, BGT226, BGT-226 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 27 mg/mL (41.5 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.37 mL | 76.85 mL | 153.7 mL |
| 0.5 mM | 3.07 mL | 15.37 mL | 30.74 mL |
| 1 mM | 1.54 mL | 7.69 mL | 15.37 mL |
| 5 mM | 0.31 mL | 1.54 mL | 3.07 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1245537-68-1 | 1245537-68-1 供应商 | 1245537-68-1 花费 | 1245537-68-1 生产商 | 订购 1245537-68-1 | 1245537-68-1 代理商