Obeticholic Acid

Name: Obeticholic Acid
SKU: A13866
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A13866

FXR 激动剂

1 篇发表文献

奥贝胆酸是一种强效且选择性的法尼酮X受体（FXR）激动剂，其半数有效浓度（EC50）为99纳摩尔。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥490.00	现货
50mg	¥665.00	现货
100mg	¥1,120.00	现货
200mg	¥1,960.00	现货
500mg	¥3,115.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Obeticholic Acid发表的1篇文献

Tomasz Kostrzewski, .et al. , Hepatol Commun, 2019, 13 November

生物活性

Discription

Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13866
分子式	C26H44O4
分子量	420.63
CAS号	459789-99-2
SMILES	CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O
其他名称	INT-747, 6-ECDCA
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	76 mg/mL (180.68 mM)
	Water	Insoluble
	Ethanol	Warmed: 76 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.77 mL	118.87 mL	237.74 mL
0.5 mM	4.75 mL	23.77 mL	47.55 mL
1 mM	2.38 mL	11.89 mL	23.77 mL
5 mM	0.48 mL	2.38 mL	4.75 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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