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Odanacatib (MK-0822)

Odanacatib (MK-0822)

Name: Odanacatib (MK-0822)
SKU: A11265

目录号: A11265

Cathepsin K 抑制剂

Odanacatib (MK-0822) Chemical Structure

CAS NO. 603139-19-1

Odanacatib (MK-0822)是组织蛋白酶K（一种参与骨吸收的酶）的抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,120.00
25 mg	￥ 1,960.00
50 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 770.00

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生物活性

Odanacatib (MK-0822)是组织蛋白酶K（一种参与骨吸收的酶）的抑制剂。

靶点信息

Cathepsin K (human)	Cathepsin K (rabbit)
0.2 nM	1 nM

溶解度 *

In vitro (25°C)	DMSO	96 mg/mL (182.66 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+corn oil	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.03 mL	95.13 mL	190.26 mL
0.5 mM	3.81 mL	19.03 mL	38.05 mL
1 mM	1.9 mL	9.51 mL	19.03 mL
5 mM	0.38 mL	1.9 mL	3.81 mL

*The above data is based on the productmolecular weight 525.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11265
作用机制	Inhibitor (抑制剂)
M. Wt	525.6
Formula	C25H27F4N3O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	603139-19-1
Synonyms	MK0822
SMILES	CC(C)(C[C@@H](C(=O)NC1(CC1)C#N)N[C@@H](C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F