ODM-203
目录号: A19098
FGFR/VEGFR 抑制剂
ODM-203 是一种强效的 FGFR 和 VEGFR 家族抑制剂,其对重组 FGFR1、FGFR2、FGFR3 和 FGFR4 的 IC50 分别为 11、16、6、35 nM,对 VEGFR1、VEGFR2 和 VEGFR3 的 IC50 分别为 26、9、5 nM。
Discription | ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. | ||
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Targets |
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目录号 | A19098 |
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分子式 | C26H21F2N5O2S |
分子量 | 505.54 |
CAS号 | 1430723-35-5 |
SMILES | CN(N=C1)C=C1C2=CC=C3C(N=CN3C4=CC(C5=CC=C(F)C=C5F)=CC(NS(C6CC6)(=O)=O)=C4)=C2 |
其他名称 | ODM203, ODM 203 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (178.02 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.78 mL | 98.9 mL | 197.81 mL |
0.5 mM | 3.96 mL | 19.78 mL | 39.56 mL |
1 mM | 1.98 mL | 9.89 mL | 19.78 mL |
5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2