OF-1

Name: OF-1
SKU: A16000
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A16000

BRPF1B/BRPF2 bromodomain inhibitor

OF-1 是一种针对 BRPF 溴结构域的化学探针。OF-1 已被证实能与 BRPF1B 结合，其 KD 为 100 nM（ITC），与 BRPF2 的 KD 为 500 nM（ITC），与 BRPF3 的 KD 为 2.4 uM（ITC）。

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规格	价格	库存
5mg	¥560.00	现货
10mg	¥840.00	现货
50mg	¥3,640.00	现货
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Data Sheet

SDS

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生物活性

Discription	OF-1 is a chemical probe for BRPF bromodomains. OF-1 has been shown to bind to BRPF1B with a KD of 100 nM (ITC), to BRPF2 with a KD of 500 nM (ITC) and to BRPF3 with a KD of 2.4 uM (ITC).

产品信息

目录号	A16000
分子式	C17H18BrN3O4S
分子量	440.31
CAS号	19973-83-4
SMILES	O=S(C1=CC=C(Br)C=C1C)(NC2=C(OC)C=C(N3C)C(N(C)C3=O)=C2)=O
其他名称	OF1, OF 1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 72 mg/mL (163.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+30%PEG300+5%Tween-80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.71 mL	113.56 mL	227.11 mL
0.5 mM	4.54 mL	22.71 mL	45.42 mL
1 mM	2.27 mL	11.36 mL	22.71 mL
5 mM	0.45 mL	2.27 mL	4.54 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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