OICR-9429
目录号: A16641
Wdr5-MLL interaction 拮抗剂
OICR-9429 是一种新型小分子拮抗剂，针对 Wdr5-MLL 交互作用，具有 5 uM 的 IC50。能够抑制增殖并诱导分化。
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生物活性
| Discription | OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50 of 5 uM. inhibit proliferation and induce differentiation . |
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产品信息
| 目录号 | A16641 |
|---|---|
| 分子式 | C29H32F3N5O3 |
| 分子量 | 555.59 |
| CAS号 | 1801787-56-3 |
| SMILES | O=C(C1=CNC(C=C1C(F)(F)F)=O)NC2=CC(C3=CC(CN4CCOCC4)=CC=C3)=CC=C2N5CCN(C)CC5 |
| 其他名称 | OICR9429, OICR 9429 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 37 mg/mL (66.59 mM) | |
| Water | Insoluble | ||
| Ethanol | 14 mg/mL (25.19 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18 mL | 89.99 mL | 179.99 mL |
| 0.5 mM | 3.6 mL | 18 mL | 36 mL |
| 1 mM | 1.8 mL | 9 mL | 18 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1801787-56-3 | 1801787-56-3 供应商 | 1801787-56-3 花费 | 1801787-56-3 生产商 | 订购 1801787-56-3 | 1801787-56-3 代理商