Olcegepant hydrochloride
目录号: A21900
CGRP1 receptor 拮抗剂
Olcegepant hydrochloride 是第一个强效且选择性的非肽类拮抗剂,针对 钙化素基因相关肽1 (CGRP1) 受体,具有 IC50 为 0.03 nM 和对人类 CGRP 的 Ki 为 14.4 pM。
Discription | Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. |
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目录号 | A21900 |
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分子式 | C38H47Br2N9O5.HCl |
分子量 | 906.11 |
CAS号 | 586368-06-1 |
SMILES | O=C1N(CC2=C(N1)C=CC=C2)C3CCN(C(N[C@@H](C(N[C@H](C(N4CCN(C5=CC=NC=C5)CC4)=O)CCCCN)=O)CC6=CC(Br)=C(C(Br)=C6)O)=O)CC3.Cl |
其他名称 | BIBN-4096 hydrochloride, BIBN4096, BIBN 4096; BIBN4096BS hydrochloride, BIBN 4096BS, BIBN-4096BS |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2