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Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.63 mL | 98.16 mL | 196.31 mL |
| 0.5 mM | 3.93 mL | 19.63 mL | 39.26 mL |
| 1 mM | 1.96 mL | 9.82 mL | 19.63 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.93 mL |
*The above data is based on the productmolecular weight 509.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13670 |
|---|---|
| 作用机制 | Stimulator (刺激物) |
| M. Wt | 509.39 |
| Formula | C21H16F5N7O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1628732-62-6 |
| Synonyms | IW-1701, IW1701, IW 1701 |
| SMILES | FC1=C(C=CC=C1)CN2C(C3=NOC=C3)=CC(C4=NC=C(F)C(NC[C@](C(N)=O)(O)C(F)(F)F)=N4)=N2 |
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