Ombitasvir (ABT-267)
目录号: A17624
HCV NS5A inhibitor
Ombitasvir 是一种强效的乙型肝炎病毒蛋白 NS5A 抑制剂,对 HCV 基因型 1 至 5 的 EC50 值为 0.82 至 19.3 pM,对基因型 6a 的 EC50 值为 366 pM。
Discription | Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A17624 |
---|---|
分子式 | C50H67N7O8 |
分子量 | 894.11 |
CAS号 | 1258226-87-7 |
SMILES | CC([C@H](NC(OC)=O)C(N1CCC[C@H]1C(NC2=CC=C([C@@H]3CC[C@@H](C4=CC=C(NC([C@@H]5CCCN5C([C@@H](NC(OC)=O)C(C)C)=O)=O)C=C4)N3C6=CC=C(C(C)(C)C)C=C6)C=C2)=O)=O)C |
其他名称 | ABT-267; ABT267; ABT 267; Ombitasvir; Viekira Pak. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 94 mg/mL (105.13 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.18 mL | 55.92 mL | 111.84 mL |
0.5 mM | 2.24 mL | 11.18 mL | 22.37 mL |
1 mM | 1.12 mL | 5.59 mL | 11.18 mL |
5 mM | 0.22 mL | 1.12 mL | 2.24 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2