(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium)

Name: (E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium)
SKU: A10673
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10673

PLK 抑制剂

ON-01910 对慢性淋巴细胞性白血病细胞具有选择性的细胞毒性，其作用机制涉及双重途径：PI3K/AKT抑制和氧化应激诱导。

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(E/Z)-Rigosertib sodium ((E/Z)-ON-01910 sodium)

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥350.00	现货
10mg	¥630.00	现货
25mg	¥1,295.00	现货
50mg	¥1,925.00	现货
100mg	¥3,325.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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Data Sheet

SDS

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生物活性

Discription

ON-01910 is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.

Targets

Target	Value

产品信息

目录号	A10673
分子式	C21H24NNaO8S
分子量	473.5
CAS号	1225497-78-8
SMILES	COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-].[Na+]
其他名称	Estybon, Novonex
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (179.52 mM)
	Water	85 mg/mL (179.52 mM)
	Ethanol	Insoluble
In vivo	water	90 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.12 mL	105.6 mL	211.19 mL
0.5 mM	4.22 mL	21.12 mL	42.24 mL
1 mM	2.11 mL	10.56 mL	21.12 mL
5 mM	0.42 mL	2.11 mL	4.22 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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