ON 146040

Name: ON 146040
SKU: A16266
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A16266

dual PI3K and BCR-ABL 抑制剂

ON 146040 是首个针对 STAT3 和 STAT5 通路的双重 PI3K 和 BCR-ABL 抑制剂；抑制 PI3K α/δ 亚型，IC50 值分别为 14/20 nM。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
5mg	¥980.00	现货
10mg	¥1,610.00	现货
25mg	¥2,660.00	现货
50mg	¥3,780.00	现货
100mg	¥5,075.00	现货
200mg	¥6,860.00	现货
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Data Sheet

SDS

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生物活性

Discription

ON 146040 is the first dual PI3K and BCR-ABL inhibitor that targets the STAT3 and STAT5 pathways; inhibits PI3K α/δ isoforms with IC50 of 14/20 nM.

Targets

Target	Value

产品信息

目录号	A16266
分子式	C24H23N7O3S
分子量	489.55
CAS号	1404231-34-0
SMILES	O=C(NC(C=NC(NC1=CC=C(N2CCN(C)CC2)C=C1)=N3)=C3S/4)C4=C\C5=CC=C([N+]([O-])=O)C=C5
其他名称	ON-146040, ON146040
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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