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Orlistat

目录号: A10676

FASN 抑制剂

1 篇发表文献

Orlistat 是一种通用的脂肪酶抑制剂，对人类十二指肠液中的 PL 的 IC50 为 122 ng/ml。Orlistat 还是脂肪酸合成酶（FASN）的抑制剂，可用于长期研究肥胖症的口服药物。具有抗动脉粥样硬化效果。

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Grouped product items
规格	价格	库存	数量
25mg	¥175.00	现货
50mg	¥245.00	现货
100mg	¥315.00	现货
200mg	¥525.00	现货
250mg	¥595.00	现货
500mg	¥875.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Orlistat发表的1篇文献

M Sugihara, .et al. , J Cell Biol, 2019, pii: jcb.201712120 PMID: 30705059

生物活性

Discription

Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity. Anti-atherosclerotic effect.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10676
分子式	C29H53NO5
分子量	495.73
CAS号	96829-58-2
SMILES	CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
其他名称	Tetrahydrolipstatin
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	97 mg/mL (195.67 mM)
	Water	Insoluble
	Ethanol	97 mg/mL (195.67 mM)
In vivo	5% DMSO+40% PEG 300+5% Tween 80+ddH2O	12 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.17 mL	100.86 mL	201.72 mL
0.5 mM	4.03 mL	20.17 mL	40.34 mL
1 mM	2.02 mL	10.09 mL	20.17 mL
5 mM	0.4 mL	2.02 mL	4.03 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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