Ketodarolutamide (ORM-15341)
目录号: A12312
human AR (hAR) antagonist
ORM-15341 是一种针对人类AR(hAR)的强效全拮抗剂,通过在稳定表达全长hAR和雄激素响应性荧光素酶报告基因构建的AR-HEK293细胞中的转激活试验显示,其 IC50 值为38 nM。
Discription | ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. | |||||
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Cell Research |
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目录号 | A12312 |
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分子式 | C19H17ClN6O2 |
分子量 | 396.83 |
CAS号 | 1297537-33-7 |
SMILES | ClC1=C(C#N)C=CC(C2=NN(C[C@H](C)NC(C3=NNC(C(C)=O)=C3)=O)C=C2)=C1 |
其他名称 | ORM15341, ORM 15341 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2