产品详情
ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.2 mL | 126 mL | 252 mL |
0.5 mM | 5.04 mL | 25.2 mL | 50.4 mL |
1 mM | 2.52 mL | 12.6 mL | 25.2 mL |
5 mM | 0.5 mL | 2.52 mL | 5.04 mL |
*The above data is based on the productmolecular weight 396.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A12312 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 396.83 |
Formula | C19H17ClN6O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1297537-33-7 |
Synonyms | ORM15341, ORM 15341 |
SMILES | ClC1=C(C#N)C=CC(C2=NN(C[C@H](C)NC(C3=NNC(C(C)=O)=C3)=O)C=C2)=C1 |
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