Ketodarolutamide (ORM-15341)

目录号: A12312
human AR (hAR) antagonist
ORM-15341 是一种针对人类AR(hAR)的强效全拮抗剂,通过在稳定表达全长hAR和雄激素响应性荧光素酶报告基因构建的AR-HEK293细胞中的转激活试验显示,其 IC50 值为38 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
5mg
¥455.00
现货
10mg
¥735.00
现货
25mg
¥1,330.00
现货
50mg
¥2,065.00
现货
100mg
¥3,185.00
现货
10mM * 1mL in DMSO
¥490.00
现货
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生物活性
Discription ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A12312
分子式 C19H17ClN6O2
分子量 396.83
CAS号 1297537-33-7
SMILES ClC1=C(C#N)C=CC(C2=NN(C[C@H](C)NC(C3=NNC(C(C)=O)=C3)=O)C=C2)=C1
其他名称 ORM15341, ORM 15341
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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