OSI-027

Name: OSI-027
SKU: A11056
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11056

mTOR 抑制剂

OSI-027 是一种强效、选择性且口服生物利用度高的 mTOR 激酶抑制剂，它抑制与 mTOR 的 TORC1 和 TORC2 复合体相关的激酶活性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥280.00	现货
5mg	¥455.00	现货
10mg	¥805.00	现货
25mg	¥1,785.00	现货
50mg	¥2,415.00	现货
100mg	¥4,130.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

OSI-027 is a potent, selective and orally bioavailable mTOR kinase inhibitor that inhibits the kinase activity associated with both the TORC1 and TORC2 complexes of mTOR.

Targets

Target	Value

产品信息

目录号	A11056
分子式	C21H22N6O3
分子量	406.4
CAS号	936890-98-1
SMILES	COC1=CC=CC2=C/C(=C/3\C4=C(N=CNN4C(=N3)C5CCC(CC5)C(=O)O)N)/N=C21
其他名称	OSI027
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	16 mg/mL (39.36 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.61 mL	123.03 mL	246.06 mL
0.5 mM	4.92 mL	24.61 mL	49.21 mL
1 mM	2.46 mL	12.3 mL	24.61 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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