微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
OSI-930是Kit，KDR，Flt，CSF-1R，c-Raf和Lck的有效抑制剂，IC50分别为80 nM，9 nM，8 nM，15 nM，41 nM和22 nM。
Targets
| Target | Value |
|---|---|
| FLT1 | IC50: 8nM |
| KDR | IC50: 9nM |
| CSF-1R | IC50: 15nM |
| LCK | IC50: 22nM |
| C-Raf | IC50: 41nM |
| Kit | IC50: 80nM |
| FLT3 | IC50: 1.303μM |
| PDGFRα | IC50: 3.408μM |
| Abl | IC50: 4.738μM |
| PDGFRβ | IC50: 6.9μM |
| EGFR | IC50: >10μM |
| AuroraA | IC50: >10μM |
| Axl | IC50: >10μM |
| CDK2/CyclinA | IC50: >10μM |
| IKKβ | IC50: >10μM |
| MEK1 | IC50: >10μM |
| PDPK1 | IC50: >10μM |
| PKBβ | IC50: >10μM |
| Tie-2 | IC50: >10μM |
| In vitro (25°C) | DMSO | 85 mg/mL (191.68 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.55 mL | 112.76 mL | 225.53 mL |
| 0.5 mM | 4.51 mL | 22.55 mL | 45.11 mL |
| 1 mM | 2.26 mL | 11.28 mL | 22.55 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.51 mL |
*The above data is based on the productmolecular weight 443.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10679 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 443.4 |
| Formula | C22H16F3N3O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 728033-96-3 |
| Synonyms | OSI930 |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Motesanib (AMG706)
Motesanib(AMG706)是一种多激酶抑制剂，可选择性靶向VEGF受体，血小板衍生的生长因子受体（PDGFRs）和Kit受体…
Vandetanib (ZD6474)
Vandetanib (ZD6474)是一种VEGFR和EGFR拮抗剂，是一种酪氨酸激酶抑制剂，对于HUVEC增殖，PC-9细胞和酪氨酸激酶活…
Telatinib (BAY 57-9352)
Telatinib (BAY 57-9352)是一种口服的血管内皮生长因子受体2和3（VEGFR2/3）和血小板衍生的生长因子受体β酪氨酸…
TSU-68 (Orantinib, SU6668)
TSU-68 (Orantinib,SU6668)在无细胞试验中具有8 nM的Ki对PDGFR自磷酸化的最大效力，但也强烈抑制Flk-1和FGFR1反磷酸…
BMS-690514
BMS-690514是一种有效的选择性表皮生长因子受体（EGFR），HER2和HER4抑制剂，以及VEGF受体激酶。
SU 5416 (Semaxinib)
SU 5416 (Semaxinib)是血管内皮生长因子受体（VEGFR）的抑制剂，它还抑制其他酪氨酸激酶KIT，MET，FLT3和RET。
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506)是一种多激酶抑制剂，IC50为17、40和69 nM c-KIT，VEGFR2，B-Raf。Regorafenib（BAY 73-4506）是一种…
Keywords:购买 OSI-930 | OSI-930 供应商 | 订购 OSI-930 | OSI-930 价格 | OSI-930 生产商 | 订单 OSI-930 | OSI-930 代理商 | 购买 728033-96-3| 728033-96-3 供应商 | 订购 728033-96-3 | 728033-96-3 价格 | 728033-96-3 生产商 | 订单 728033-96-3 | 728033-96-3 代理商|buy OSI-930 | OSI-930 Supplier | purchase OSI-930 | OSI-930 cost | OSI-930 manufacturer | order OSI-930 | OSI-930 distributor | buy 728033-96-3| 728033-96-3 Supplier | purchase 728033-96-3 | 728033-96-3 cost | 728033-96-3 manufacturer | order 728033-96-3 | 728033-96-3 distributor