Birabresib (OTX015)

Name: Birabresib (OTX015)
SKU: A13890
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A13890

BET 抑制剂

OTX015 是一种口服生物利用度高的小分子抑制剂，针对 BRD2、BRD3 和 BRD4（EC50s = 10-19 nM）。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥560.00	现货
25mg	¥1,050.00	现货
50mg	¥1,680.00	现货
100mg	¥2,870.00	现货
200mg	¥4,305.00	现货
500mg	¥6,895.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

OTX015 is an orally bioavailable, small molecule inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10-19 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13890
分子式	C25H22ClN5O2S
分子量	491.99
CAS号	202590-98-5
SMILES	CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
其他名称	OTX 015, OTX-015
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	89 mg/mL (180.9 mM)
	Water	Insoluble
	Ethanol	89 mg/mL
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.33 mL	101.63 mL	203.26 mL
0.5 mM	4.07 mL	20.33 mL	40.65 mL
1 mM	2.03 mL	10.16 mL	20.33 mL
5 mM	0.41 mL	2.03 mL	4.07 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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