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Oxprenolol HCl

Oxprenolol HCl

Name: Oxprenolol HCl
SKU: A17368

目录号: A17368

Non-selective β antagonist

Oxprenolol HCl Chemical Structure

CAS NO. 6452-73-9

Oxprenolol is an orally bioavailable β-adrenergic receptor (β-AR) antagonist (Ki = 7.10 nM in a radioligand binding assay using rat heart tissue). It is non-selective and inhibits both β1- and β2-ARs (Kds = 2.09 and 1.35 nM in isolated rat heart and uterus, respectively). Oxprenolol is selective for β-ARs over serotonin (5-HT) receptors in rat sarcolemmal membrane preparations (IC50s = 4.13 and 23,300 nM, respectively), but it binds to 5-HT1A receptors in rat hippocampus and 5-HT1B in rat striatum (Kis = 94.2 and 642 nM, respectively).

库存：现货

规格	价格	数量
100 mg	￥ 350.00
500 mg	￥ 1,400.00

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制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.13 mL	165.67 mL	331.33 mL
0.5 mM	6.63 mL	33.13 mL	66.27 mL
1 mM	3.31 mL	16.57 mL	33.13 mL
5 mM	0.66 mL	3.31 mL	6.63 mL

*The above data is based on the productmolecular weight 301.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17368
作用机制	Antagonist (拮抗剂)
M. Wt	301.81
Formula	C15H24ClNO3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	6452-73-9
Synonyms	Oxprenolol hydrochloride; Coretal; Dialicor; Rixiprol; Trasicor; Evinrozit; Ranidrox; Oxprenolol HCl; Trepress; Vrachor; Ba 39089; Ba-39089; Ba39089
SMILES	OC(CNC(C)C)COC1=CC=CC=C1OCC=C.[H]Cl