P276-00

Name: P276-00
SKU: A13547
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A13547

CDK 抑制剂

P276-00 是一种新型的 CDK1、CDK4 和 CDK9 抑制剂，其半抑制浓度（IC50）分别为 79 nM、63 nM 和 20 nM。目前处于第二/三期

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥595.00	现货
10mg	¥980.00	现货
25mg	¥1,855.00	现货
50mg	¥3,010.00	现货
100mg	¥5,460.00	现货
*10mM 1mL in DMSO**	¥595.00	现货
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Data Sheet

SDS

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生物活性

Discription

P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. In Phase 2/3

Targets

Target	Value

产品信息

目录号	A13547
分子式	C21H20ClNO5.HCl
分子量	438.3
CAS号	920113-03-7
SMILES	CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
其他名称	P276, P276-00
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	79 mg/mL (180.24 mM)
	Water	79 mg/mL (180.24 mM)
	Ethanol	6 mg/mL (13.69 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.82 mL	114.08 mL	228.15 mL
0.5 mM	4.56 mL	22.82 mL	45.63 mL
1 mM	2.28 mL	11.41 mL	22.82 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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