PAC-1
PAC-1 是一种激活 procaspase-3 的化合物，能够在癌细胞中诱导凋亡，其半数有效浓度（EC50）为 2.08 微摩尔。
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生物活性
| Discription | PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11090 |
|---|---|
| 分子式 | C23H28N4O2 |
| 分子量 | 392.5 |
| CAS号 | 315183-21-2 |
| SMILES | C=CCC1=CC=C/C(=C/NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)/C1=O |
| 其他名称 | PAC1,first procaspase activating compound |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 75 mg/mL (191.09 mM) | |
| Water | Insoluble | ||
| Ethanol | 15 mg/mL (38.21 mM) | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.48 mL | 127.39 mL | 254.78 mL |
| 0.5 mM | 5.1 mL | 25.48 mL | 50.96 mL |
| 1 mM | 2.55 mL | 12.74 mL | 25.48 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 315183-21-2 | 315183-21-2 供应商 | 315183-21-2 花费 | 315183-21-2 生产商 | 订购 315183-21-2 | 315183-21-2 代理商