PROTAC ERα Degrader-5 (PAC)

Name: PROTAC ERα Degrader-5 (PAC)
SKU: A12939
Price: 5740 CNY
Rating: 5 (288 reviews)

目录号: A12939

PAC，包含 ADCs 连接器和 PROTACs，与抗体结合。PAC 来自专利 WO2017201449A1，化合物 LP2。与抗体结合的 PAC 是比 PROTAC（无抗体）更显著的雌激素受体-α (ERα) 降解剂。

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规格	价格	库存
1mg	¥5,740.00	现货
5mg	¥12,740.00	现货
10mg	¥20,860.00	现货
50mg	¥68,740.00	现货
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Data Sheet

SDS

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生物活性

Discription	PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

产品信息

目录号	A12939
分子式	C94H107N13O16
分子量	1674.93
CAS号	2158322-33-7
SMILES	CN(C(COCCOCCNC(C1=CC=C(C(N2[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC3=C(OC)C=CC4=C3C=CC=C4)C5=C2C=C(C#N)C=C5)=O)=O)C=C1)=O)=O)CCOC(C=C6)=CC=C6/C(C7=CC=C(OCC(C=C8)=CC=C8NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)C=C7)=C(C%10=CC=CC=C%10)/CC
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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