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PAC

PAC

Name: PAC
SKU: A12939

目录号: A12939

PAC Chemical Structure

CAS NO. 2158322-33-7

PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

库存：现货

规格	价格	数量
1 mg	￥ 13,860.00
5 mg	￥ 41,580.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	5.97 mL	29.85 mL	59.7 mL
0.5 mM	1.19 mL	5.97 mL	11.94 mL
1 mM	0.6 mL	2.99 mL	5.97 mL
5 mM	0.12 mL	0.6 mL	1.19 mL

*The above data is based on the productmolecular weight 1674.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12939
M. Wt	1674.93
Formula	C94H107N13O16
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2158322-33-7
SMILES	CN(C(COCCOCCNC(C1=CC=C(C(N2[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC3=C(OC)C=CC4=C3C=CC=C4)C5=C2C=C(C#N)C=C5)=O)=O)C=C1)=O)=O)CCOC(C=C6)=CC=C6/C(C7=CC=C(OCC(C=C8)=CC=C8NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)C=C7)=C(C%10=CC=CC=C%10)/CC