Paclitaxel (Taxol)

Name: Paclitaxel (Taxol)
SKU: A10689

目录号: A10689

Microtubule Associated 抑制剂

Product Citations (5)

Paclitaxel (Taxol) Chemical Structure

CAS NO. 33069-62-4

Paclitaxel (Taxol)是一种有丝分裂抑制剂，可稳定微管，从而干扰细胞分裂过程中微管的正常分解，在人内皮细胞中IC50为0.1pM。

库存：现货

规格	价格	数量
10 mg	￥ 210.00
50 mg	￥ 350.00
100 mg	￥ 560.00
200 mg	￥ 700.00
10mM * 1mL in DMSO	￥ 350.00

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生物活性

Paclitaxel (Taxol)是一种有丝分裂抑制剂，可稳定微管，从而干扰细胞分裂过程中微管的正常分解，在人内皮细胞中IC50为0.1pM。

靶点信息

Microtubule (human endothelial cells)
0.1 pM

溶解度 *

In vitro (25°C)	DMSO	152 mg/mL (178 mM)
	Water	Insoluble
	Ethanol	16 mg/mL (18.73 mM)
In vivo	5% DMSO+40% PEG 300+5% Tween 80+ddH2O	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.71 mL	58.55 mL	117.11 mL
0.5 mM	2.34 mL	11.71 mL	23.42 mL
1 mM	1.17 mL	5.86 mL	11.71 mL
5 mM	0.23 mL	1.17 mL	2.34 mL

*The above data is based on the productmolecular weight 853.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10689
作用机制	Inhibitor (抑制剂)
M. Wt	853.9
Formula	C47H51NO14
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	33069-62-4
Synonyms	Taxol
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C