Parbendazole
目录号: A18981
Microtubule assembly 抑制剂
Parbendazole 是一种强效的微管组装抑制剂,能够破坏微管蛋白,其半抑制浓度(EC50)为8.79纳摩尔,并显示出广谱的驱虫活性。
Discription | Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 8.79?nM, and exhibits a broad-spectrum anthelmintic activity. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A18981 |
---|---|
分子式 | C13H17N3O2 |
分子量 | 247.29 |
CAS号 | 14255-87-9 |
SMILES | O=C(OC)NC1=NC2=CC=C(CCCC)C=C2N1 |
其他名称 | SKF 29044, SKF29044, SKF-29044 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 3 mg/mL (12.13 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 40.44 mL | 202.19 mL | 404.38 mL |
0.5 mM | 8.09 mL | 40.44 mL | 80.88 mL |
1 mM | 4.04 mL | 20.22 mL | 40.44 mL |
5 mM | 0.81 mL | 4.04 mL | 8.09 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2