Paritaprevir (ABT-450)
目录号: A17625
HCV NS3/4A inhibitor
Paritaprevir(ABT-450)是一种强效的非结构蛋白3/4A(NS3/4A)蛋白酶抑制剂,其对HCV 1a和1b的EC50分别为1 nM和0.21 nM。
Discription | Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. |
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目录号 | A17625 |
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分子式 | C40H43N7O7S |
分子量 | 765.88 |
CAS号 | 1216941-48-8 |
SMILES | O=C([C@]([C@]1([H])/C=C\CCCCC[C@@H]2NC(C3=NC=C(C)N=C3)=O)(C1)NC([C@@](C[C@@H](OC4=C5C=CC=CC5=C(C=CC=C6)C6=N4)C7)([H])N7C2=O)=O)NS(=O)(C8CC8)=O |
其他名称 | ATB450; ABT-450; ABT 450; Paritaprevir; Veruprevir; Brand name: VIEKIRA PAK. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 97 mg/mL (126.64 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 13.06 mL | 65.28 mL | 130.57 mL |
0.5 mM | 2.61 mL | 13.06 mL | 26.11 mL |
1 mM | 1.31 mL | 6.53 mL | 13.06 mL |
5 mM | 0.26 mL | 1.31 mL | 2.61 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2