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Parthenolide ((-)-Parthenolide)

Parthenolide ((-)-Parthenolide)

Name: Parthenolide ((-)-Parthenolide)
SKU: A10698

目录号: A10698

Parthenolide ((-)-Parthenolide) Chemical Structure

CAS NO. 20554-84-1

Parthenolide ((-)-Parthenolide), Nuclear Factor-κB抑制剂，可特异性地耗尽HDAC1蛋白，而不影响其他I/II类 HDACs。促进MDM2的泛素化并激活p53的细胞功能。

库存：现货

规格	价格	数量
500 mg	￥ 1,400.00
100 mg	￥ 455.00
200 mg	￥ 700.00
10mM * 1mL in DMSO	￥ 427.00

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生物活性

Parthenolide ((-)-Parthenolide), Nuclear Factor-κB抑制剂，可特异性地耗尽HDAC1蛋白，而不影响其他I/II类 HDACs。促进MDM2的泛素化并激活p53的细胞功能。

靶点信息

HDAC1

溶解度 *

In vitro (25°C)	DMSO	49 mg/mL (197.32 mM)
	Water	Insoluble
	Ethanol	Warmed: 49 mg/mL (197.32 mM)
In vivo	2% DMSO+corn oil	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.27 mL	201.37 mL	402.74 mL
0.5 mM	8.05 mL	40.27 mL	80.55 mL
1 mM	4.03 mL	20.14 mL	40.27 mL
5 mM	0.81 mL	4.03 mL	8.05 mL

*The above data is based on the productmolecular weight 248.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10698
作用机制	Inhibitor (抑制剂)
M. Wt	248.3
Formula	C15H20O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	20554-84-1
SMILES	C/C/1=C/CC[C@@]2([C@H](O2)[C@@H]3[C@@H](CC1)C(=C)C(=O)O3)C