Pazopanib (GW-786034)

Name: Pazopanib (GW-786034)
SKU: A11518
Price: 245 CNY
Rating: 5 (3 reviews)

目录号: A11518

VEGFR 抑制剂

3 篇发表文献

Pazopanib 是一种强效且选择性的多靶点受体酪氨酸激酶抑制剂，能够抑制 VEGFR-1、VEGFR-2、VEGFR-3、PDGFR-a/β 和 c-kit，从而阻断肿瘤生长并抑制血管生成。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥245.00	现货
25mg	¥280.00	现货
50mg	¥490.00	现货
100mg	¥910.00	现货
200mg	¥1,680.00	现货
500mg	¥2,380.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Pazopanib (GW-786034)发表的3篇文献

Koide H, .et al. , Xenobiotica, 2018, Oct;48(10):1059-1071 PMID: 29034773

Ellawatty WEA, .et al. , Drug Metab Dispos, 2018, Jan;46(1):33-40 PMID: 29089306

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

生物活性

Discription

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11518
分子式	C21H23N7O2S
分子量	437.5
CAS号	444731-52-6
SMILES	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
其他名称	GW 786034, Votrient,GW786034
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 84 mg/mL (191.98 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.86 mL	114.29 mL	228.57 mL
0.5 mM	4.57 mL	22.86 mL	45.71 mL
1 mM	2.29 mL	11.43 mL	22.86 mL
5 mM	0.46 mL	2.29 mL	4.57 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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