PD-0332991 HCl (Palbociclib HCl)

Name: PD-0332991 HCl (Palbociclib HCl)
SKU: A10701
Price: 175 CNY
Rating: 5 (4 reviews)

目录号: A10701

CDK 4/6 抑制剂

4 篇发表文献

PD 0332991 HCl 是一种口服可用的吡啶并嘧啶衍生的环依赖性激酶 (CDK) 抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥280.00	现货
10mg	¥385.00	现货
25mg	¥560.00	现货
50mg	¥665.00	现货
100mg	¥910.00	现货
250mg	¥1,260.00	现货
500mg	¥2,240.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PD-0332991 HCl (Palbociclib HCl)发表的4篇文献

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Hiroki Ozawa, .et al. , Transl Oncol, 2022, Feb;16:101307 PMID: 34902741

Cong Li, .et al. , Mol Cancer Ther., 2015, Feb;14(2):375-83. PMID: 25487917

Pirita Pekkonen, .et al. , Cell Cycle, 2014, Dec 1; 13(23): 3670-3684 PMID: 25483078

生物活性

Discription

PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A10701
分子式	C24H29N7O2.HCl
分子量	484
CAS号	827022-32-2
SMILES	CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 3 mg/mL (6.19 mM)
	Water	30 mg/mL (61.98 mM)
	Ethanol	Insoluble
In vivo	Saline	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.66 mL	103.31 mL	206.61 mL
0.5 mM	4.13 mL	20.66 mL	41.32 mL
1 mM	2.07 mL	10.33 mL	20.66 mL
5 mM	0.41 mL	2.07 mL	4.13 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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