PD 0332991 Isethionate

Name: PD 0332991 Isethionate
SKU: A13811
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A13811

CDK4/6 抑制剂

1 篇发表文献

PD 0332991 Isethionate 是一种高度选择性的 CDK4/6 抑制剂，其 IC50 分别为 11 nM/16 nM。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥735.00	现货
50mg	¥735.00	现货
100mg	¥1,085.00	现货
200mg	¥1,365.00	现货
500mg	¥2,870.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PD 0332991 Isethionate发表的1篇文献

K Keegan ,etc. Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia. Molecular cancer therapeutics, 2014, 13(4), 880-889.

生物活性

Discription

PD 0332991 Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM respectively.

Targets

Target	Value

产品信息

目录号	A13811
分子式	C26H35N7O6S
分子量	573.7
CAS号	827022-33-3
SMILES	CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O
其他名称	PD0332991, PD-0332991
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Insoluble
	Water	Warmed: 9 mg/mL (15.69 mM)
	Ethanol	Insoluble
In vivo	saline (with warming)	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.43 mL	87.15 mL	174.31 mL
0.5 mM	3.49 mL	17.43 mL	34.86 mL
1 mM	1.74 mL	8.72 mL	17.43 mL
5 mM	0.35 mL	1.74 mL	3.49 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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