PD 90780
目录号: A19821
NGF 拮抗剂
PD 90780 是一种非肽类拮抗剂,用于抑制神经生长因子(NGF)与 P75 NGF 受体的结合,能够抑制 NGF-p75 NTR 之间的相互作用,其在 PC12 细胞和 PC12 nnr5 细胞中的 IC50 值分别为 23.1 μM 和 1.8 μM。
Discription | PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 ?M and 1.8 ?M in PC12 cells and PC12 nnr5 cells, respectively . |
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目录号 | A19821 |
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分子式 | C19H14N4O4 |
分子量 | 362.34 |
CAS号 | 77422-99-2 |
SMILES | CN1C2=CC(C(O)=O)=NN2C(C3=CC(NC(C4=CC=CC=C4)=O)=CC=C13)=O |
其他名称 | PD-90780, PD90780 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2