Mirdametinib (PD0325901)

Name: Mirdametinib (PD0325901)
SKU: A10256
Price: 280 CNY
Rating: 5 (6 reviews)

目录号: A10256

MEK 抑制剂

6 篇发表文献

PD0325901 是一种 MEK 抑制剂，并且与 ATP 非竞争性，对激活的 MEK1 和 MEK2 的 Kiapp 为 1 nM。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥840.00	现货
50mg	¥1,260.00	现货
100mg	¥1,960.00	现货
200mg	¥2,940.00	现货
500mg	¥4,830.00	现货
1g	¥6,580.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Mirdametinib (PD0325901)发表的6篇文献

Tadaaki Nakajima, .et al. , FEBS Open Bio, 2024, Jan;14(1):37-50 PMID: 37953493

Jan Langkabel, .et al. , bioRxiv, 2021, January 25

Ryan Clarke, .et al. , Mol Cell, 2021, Jan 21;81(2):226-238.e5 PMID: 33378644

Tzeng SF, .et al. , FASEB J, 2018, Jun 15:fj201800687 PMID: 29906246

Fukumoto S, .et al. , Acta Histochem, 2018, Feb;120(2):142-150 PMID: 29397960

Yoshiteru Yano, .et al. , Regenerative Therapy, 2016, 3 (2016) 1-6

生物活性

Discription

PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10256
分子式	C16H14F3IN2O4
分子量	482.2
CAS号	391210-10-9
SMILES	C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOC[C@@H](CO)O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	89 mg/mL (184.57 mM)
	Water	Insoluble
	Ethanol	37 mg/mL (76.73 mM)
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.74 mL	103.69 mL	207.38 mL
0.5 mM	4.15 mL	20.74 mL	41.48 mL
1 mM	2.07 mL	10.37 mL	20.74 mL
5 mM	0.41 mL	2.07 mL	4.15 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 Mirdametinib (PD0325901) | Mirdametinib (PD0325901) 供应商 | Mirdametinib (PD0325901) 花费 | Mirdametinib (PD0325901) 生产商 | 订购 Mirdametinib (PD0325901) | Mirdametinib (PD0325901) 代理商 | 购买 391210-10-9 | 391210-10-9 供应商 | 391210-10-9 花费 | 391210-10-9 生产商 | 订购 391210-10-9 | 391210-10-9 代理商