PD146176 (NSC168807)
目录号: A13347
15-LO inhibitor
PD146176 (NSC168807) 是一种 15-脂氧合酶(15-LO)抑制剂,能够抑制兔网织红细胞的 15-LO,其抑制常数 Ki 为 197 nM。PD146176 (NSC168807) 在减少动脉粥样硬化方面具有显著效果。
Discription | PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis. | |||||
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Cell Research |
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目录号 | A13347 |
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分子式 | C15H11NS |
分子量 | 237.32 |
CAS号 | 4079-26-9 |
SMILES | C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4 |
其他名称 | PD 146176, PD-146176, NSC 168807, NSC-168807 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 40 mg/mL (168.54 mM) | |
Water | Insoluble | ||
Ethanol | 17 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 42.14 mL | 210.69 mL | 421.37 mL |
0.5 mM | 8.43 mL | 42.14 mL | 84.27 mL |
1 mM | 4.21 mL | 21.07 mL | 42.14 mL |
5 mM | 0.84 mL | 4.21 mL | 8.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2