微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
PD153035 (HCl salt)是EGFR酪氨酸激酶活性的极其有效和特异的抑制剂。
靶点信息
| EGFR (Cell-free assay) | EGFR (Cell-free assay) | |||
| 5.2 pM(Ki) | 5.2 pM(Ki) |
| In vitro (25°C) | DMSO | 0.46 mg/mL (1.16 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.21 mL | 126.04 mL | 252.08 mL |
| 0.5 mM | 5.04 mL | 25.21 mL | 50.42 mL |
| 1 mM | 2.52 mL | 12.6 mL | 25.21 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.04 mL |
*The above data is based on the productmolecular weight 396.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10702 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 396.7 |
| Formula | C16H14BrN3O2.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 183322-45-4 |
| Synonyms | ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271, PD-153035 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Canertinib (CI-1033)
Canertinib (CI-1033)是一种不可逆的酪氨酸激酶抑制剂，对EGFR（IC50 0.8 nM），HER-2（IC50 19 nM）和ErbB-4（IC50 7 nM）…
AG-18 (Tyrphostin 23)
AG-18 (Tyrphostin 23)是人表皮癌细胞系A431中的表皮生长因子（EGF）受体激酶抑制剂，IC50值为35M。
ARRY-543 (Varlitinib, ASLAN001)
ARRY-543 (Varlitinib,ASLAN001)是一种新型口服ErbB家族抑制剂，与批准的ErbB抑制剂不同，它直接或间接靶向ErbB家…
Pelitinib (EKB-569)
Pelitinib (EKB-569)是一种有效的,不可逆EGFR抑制剂,IC50为38.5 nM
XL647 (Tesevatinib)
XL647 (Tesevatinib)是一种口服生物可利用的小分子RTK抑制剂，可结合并抑制在肿瘤细胞增殖和肿瘤血管形成中…
ASP8273 (Naquotinib)
ASP8273 (Naquotinib)是不可逆的，第三代，选择性突变的表皮生长因子受体（EGFR）抑制剂，具有潜在的抗肿瘤…
Keywords:购买 PD153035 (HCl salt) | PD153035 (HCl salt) 供应商 | 订购 PD153035 (HCl salt) | PD153035 (HCl salt) 价格 | PD153035 (HCl salt) 生产商 | 订单 PD153035 (HCl salt) | PD153035 (HCl salt) 代理商 | 购买 183322-45-4| 183322-45-4 供应商 | 订购 183322-45-4 | 183322-45-4 价格 | 183322-45-4 生产商 | 订单 183322-45-4 | 183322-45-4 代理商|buy PD153035 (HCl salt) | PD153035 (HCl salt) Supplier | purchase PD153035 (HCl salt) | PD153035 (HCl salt) cost | PD153035 (HCl salt) manufacturer | order PD153035 (HCl salt) | PD153035 (HCl salt) distributor | buy 183322-45-4| 183322-45-4 Supplier | purchase 183322-45-4 | 183322-45-4 cost | 183322-45-4 manufacturer | order 183322-45-4 | 183322-45-4 distributor