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PD158780是一种非常有效的EGFR抑制剂，IC50为0.08 nM。泛特异性的ErbB受体拮抗剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.29 mL | 151.43 mL | 302.87 mL |
| 0.5 mM | 6.06 mL | 30.29 mL | 60.57 mL |
| 1 mM | 3.03 mL | 15.14 mL | 30.29 mL |
| 5 mM | 0.61 mL | 3.03 mL | 6.06 mL |
*The above data is based on the productmolecular weight 330.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16254 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 330.18 |
| Formula | C14H12BrN5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 171179-06-9 |
| Synonyms | PD-158780 |
| SMILES | CNC1=NC=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br |
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