Pemigatinib
目录号: A20312
FGFR inhibitor
Pemigatinib 是一种选择性的 FGFR 抑制剂,正在开发中,用于治疗患有胆管癌的患者。
Discription | Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A20312 |
---|---|
分子式 | C24H27F2N5O4 |
分子量 | 487.5 |
CAS号 | 1513857-77-6 |
SMILES | CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4 |
其他名称 | INCB054828; INCB-054828; INCB 054828; INCB54828; INCB 54828; INCB-54828 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 38 mg/mL (77.95 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.51 mL | 102.56 mL | 205.13 mL |
0.5 mM | 4.1 mL | 20.51 mL | 41.03 mL |
1 mM | 2.05 mL | 10.26 mL | 20.51 mL |
5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2