Peretinoin
目录号: A18229
SPHK inhibitor
Peretinoin，也被称为 NIK-333，是一种口服的非环状视黄酸类药物，具有潜在的抗肿瘤和化学预防活性。Peretinoin 结合并激活核内视黄酸受体（RAR），这些受体随后招募共激活蛋白，并与其他转录复合体一起促进目标基因的转录。因此，这种药物可能调节涉及细胞增殖、细胞分化和正常及肿瘤细胞凋亡的基因表达。
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生物活性
| Discription | Peretinoin, also known as NIK-333 , orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells. |
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产品信息
| 目录号 | A18229 |
|---|---|
| 分子式 | C20H30O2 |
| 分子量 | 302.45 |
| CAS号 | 81485-25-8 |
| SMILES | C/C(C)=C/CC/C(C)=C/CC/C(C)=C/C=C/C(C)=C/C(O)=O |
| 其他名称 | Peretinoin; NIK333 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 81485-25-8 | 81485-25-8 供应商 | 81485-25-8 花费 | 81485-25-8 生产商 | 订购 81485-25-8 | 81485-25-8 代理商