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Perifosine (也为KRX-0401) 充当Akt抑制剂和PI3K抑制剂。
靶点信息
| Akt (MM.1S cells) | ||||
| 4.7 μM |
| In vitro (25°C) | DMSO | Insoluble | |
| Water | 85 mg/mL (184.11mM) | ||
| Ethanol | 85 mg/mL (184.11mM) | ||
| In vivo | water | 7 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.66 mL | 108.3 mL | 216.59 mL |
| 0.5 mM | 4.33 mL | 21.66 mL | 43.32 mL |
| 1 mM | 2.17 mL | 10.83 mL | 21.66 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
*The above data is based on the productmolecular weight 461.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10709 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 461.7 |
| Formula | C25H52NO4P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 157716-52-4 |
| Synonyms | KRX-0401,NSC 639966 |
| SMILES | CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C |
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