Pexidartinib (PLX3397)

Name: Pexidartinib (PLX3397)
SKU: A15520
Price: 245 CNY
Rating: 5 (5 reviews)

目录号: A15520

CSF1/Kit/FLT3 抑制剂

5 篇发表文献

Pexidartinib 是一种小分子受体酪氨酸激酶（RTK）抑制剂，针对 KIT、CSF1R 和 FLT3，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥350.00	现货
25mg	¥560.00	现货
50mg	¥805.00	现货
100mg	¥1,050.00	现货
200mg	¥1,435.00	现货
500mg	¥2,520.00	现货
1g	¥4,900.00	现货
2g	¥8,260.00	现货
5g	¥17,920.00	现货
10g	¥25,760.00	现货
20g	¥46,340.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Pexidartinib (PLX3397)发表的5篇文献

Lu Luo, .et al. , J Neuroinflammation, 2022, Jun 11;19(1):141 PMID: 35690810

Sarah R Anderson,, .et al. , bioRxiv, 2022, 01.05.475126

Hannah D Mason, .et al. , JCI Insight, 2021, Oct 8;6(19):e149229 PMID: 34428178

Chritica Lodder, .et al. , Acta Neuropathol Commun, 2021, Jun 8;9(1):108 PMID: 34103079

Anderson SR, .et al. , Cell Rep, 2019, May 14;27(7):2002-2013.e5 PMID: 31091440

生物活性

Discription

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15520
分子式	C20H15ClF3N5
分子量	417.81
CAS号	1029044-16-3
SMILES	FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
其他名称	PLX-3397, PLX 3397
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	71 mg/mL (169.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+45% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.93 mL	119.67 mL	239.34 mL
0.5 mM	4.79 mL	23.93 mL	47.87 mL
1 mM	2.39 mL	11.97 mL	23.93 mL
5 mM	0.48 mL	2.39 mL	4.79 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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