PF-04418948
目录号: A12894
EP2 Receptor 拮抗剂
PF-04418948 是一种强效且选择性的前列腺素 EP2 受体拮抗剂,其 IC50 为 16 nM。目前处于 第一阶段 临床试验。
Discription | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. | ||
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Targets |
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目录号 | A12894 |
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分子式 | C23H20FNO5 |
分子量 | 409.41 |
CAS号 | 1078166-57-0 |
SMILES | O=C(C1(COC2=CC=C3C=C(OC)C=CC3=C2)CN(C(C4=CC=C(C=C4)F)=O)C1)O |
其他名称 | PF04418948, PF 04418948 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 80 mg/mL (195.4 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.43 mL | 122.13 mL | 244.25 mL |
0.5 mM | 4.89 mL | 24.43 mL | 48.85 mL |
1 mM | 2.44 mL | 12.21 mL | 24.43 mL |
5 mM | 0.49 mL | 2.44 mL | 4.89 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2