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PF-04447943是一种有效的选择性脑渗透pde9抑制剂，在大鼠和小鼠的多种认知模型中增加海马突触可塑性的指标并改善认知功能。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.29 mL | 126.44 mL | 252.87 mL |
| 0.5 mM | 5.06 mL | 25.29 mL | 50.57 mL |
| 1 mM | 2.53 mL | 12.64 mL | 25.29 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.06 mL |
*The above data is based on the productmolecular weight 395.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13121 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 395.46 |
| Formula | C20H25N7O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1082744-20-4 |
| Synonyms | PF04447943, PF 04447943 |
| SMILES | C[C@@H]1CN(C[C@H]1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5 |
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