PF-04457845

Name: PF-04457845
SKU: A15209
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A15209

FAAH inhibitor

PF-04457845 是一种高效且极具选择性的 FAAH 抑制剂，其 IC50 为 7.2 nM，并在动物研究中显示出与拿普洛辛相当的镇痛和抗炎效果。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥280.00	现货
10mg	¥525.00	现货
25mg	¥1,120.00	现货
50mg	¥1,680.00	现货
100mg	¥3,045.00	现货
200mg	¥3,955.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

产品信息

目录号	A15209
分子式	C23H20F3N5O2
分子量	455.43
CAS号	1020315-31-4
SMILES	C1CN(CCC1=CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=NN=CC=C4
其他名称	PF 04457845, PF04457845
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (197.61 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (8.78 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.96 mL	109.79 mL	219.57 mL
0.5 mM	4.39 mL	21.96 mL	43.91 mL
1 mM	2.2 mL	10.98 mL	21.96 mL
5 mM	0.44 mL	2.2 mL	4.39 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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