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PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.55 mL | 97.73 mL | 195.47 mL |
| 0.5 mM | 3.91 mL | 19.55 mL | 39.09 mL |
| 1 mM | 1.95 mL | 9.77 mL | 19.55 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.91 mL |
*The above data is based on the productmolecular weight 511.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18659 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 511.59 |
| Formula | C25H36F3N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1228111-63-4 |
| Synonyms | PF-04634817; PF 04634817; PF04634817; PF-4634817; PF 4634817; PF4634817. |
| SMILES | O=C([C@]1(C(C)C)C[C@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3[C@](C4)([H])CN(C5=NC=NC(C(F)(F)F)=C5)[C@]4([H])C3 |
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