PF-05175157

Name: PF-05175157
SKU: A21460
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A21460

ACC 抑制剂

PF-05175157 是一种广谱 乙酰辅酶A羧化酶 (ACC) 抑制剂，其半抑制浓度（IC50）分别为：人类 ACC1 为 27.0 nM，人类 ACC2 为 33.0 nM，大鼠 ACC1 为 23.5 nM，大鼠 ACC2 为 50.4 nM。

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Grouped product items
规格	价格	库存
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,295.00	现货
50mg	¥2,205.00	现货
100mg	¥4,095.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21460
分子式	C23H27N5O2
分子量	405.49
CAS号	1301214-47-0
SMILES	O=C1CC2(CCN(C(C3=CC=C4C(NC(C)=N4)=C3)=O)CC2)CC5=C1N(C(C)C)N=C5
其他名称	PF05175157, PF 05175157
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	28 mg/mL (69.05 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.66 mL	123.31 mL	246.62 mL
0.5 mM	4.93 mL	24.66 mL	49.32 mL
1 mM	2.47 mL	12.33 mL	24.66 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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