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PF-06263276

目录号: A12572
pan-JAK 抑制剂
PF-06263276(PF 6263276)是一种强效且选择性的全面JAK抑制剂,其IC50分别为JAK1的2.2 nM、JAK2的23.1 nM、JAK3的59.9 nM和TYK2的29.7 nM。
Grouped product items
规格 价格 库存 数量
2mg
¥595.00
现货
5mg
¥1,225.00
现货
10mg
¥2,135.00
现货
25mg
¥4,060.00
现货
50mg
¥5,180.00
现货
100mg
¥8,295.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PF-06263276 (PF 6263276) is a potent and selective pan-JAK inhibitor, with IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3 and TYK2, respectively.
Targets
Target Value
产品信息
目录号 A12572
分子式 C31H31FN8O2
分子量 566.63
CAS号 1421502-62-6
SMILES FC1=C(O)C=C(CC)C(C2=CC(NN=C3C4=NC5=C(CN(C(C6=NC=C(N7CCCCC7)N=C6)=O)CC5)N4)=C3C=C2)=C1
其他名称 PF06263276, PF 06263276
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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