PF-06471553

Name: PF-06471553
SKU: A12640
Price: 3115 CNY
Rating: 5 (288 reviews)

目录号: A12640

MGAT3 抑制剂

PF-06471553 是一种强效、选择性且可口服的单酰基甘油酰基转移酶3（MGAT3）抑制剂，其半抑制浓度（IC50）为92纳摩尔。

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规格	价格	库存
5mg	¥3,115.00	现货
10mg	¥5,390.00	现货
25mg	¥10,115.00	现货
50mg	¥13,195.00	现货
100mg	¥19,565.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-06471553 is a potent, selective and orally available monoacylglycerol acyltransferase 3 (MGAT3) inhibitor, with an IC50 of 92 nM.

Cell Research

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Cell Line	Type	Value	Description	References
HEK293	IC50	205 nM	Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of DGAT1 inhibitor PF-04620110 and DGAT2 inhibitor PF-06424439	[PMID: 26258602]

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产品信息

目录号	A12640
分子式	C23H25N5O4S
分子量	467.54
CAS号	1808094-07-6
SMILES	O=S(C1=CC2=C(CN(C(CC3=CC=CC(OC)=C3)=O)C2)C=C1)(NC4=NN(C5CCC5)N=C4)=O
其他名称	PF06471553, PF 06471553
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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