Ritlecitinib (PF-06651600)
目录号: A16803
JAK3 抑制剂
PF-06651600 是一种强效且不可逆的 JAK3-选择性抑制剂,其 IC50 为 33.1 nM,但对 JAK1、JAK2 和 TYK2 没有活性(IC50 > 10,000 nM)。
Discription | PF-06651600 is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2. | |||||
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Cell Research |
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目录号 | A16803 |
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分子式 | C15H19N5O |
分子量 | 285.34 |
CAS号 | 1792180-81-4 |
SMILES | C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O |
其他名称 | PF06651600, PF 06651600 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2